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Discovery & Development
Technologies

Discovery & Development
Technologies

Who we are

EMD Serono is the North America biopharmaceutical business of Merck, KGaA, Darmstadt, Germany—a leading science and technology company. We aspire to create, improve and prolong life for people living with difficult-to treat conditions like multiple sclerosis, cancer and infertility.

Where we are

Located in the Greater Boston area, our Discovery & Development Technologies (DDTech) team is passionate about developing drugs for patients with difficult-to-treat diseases. We have strong expertise in three therapeutic modalities: small molecules, therapeutic antibodies and antibody drug conjugates.

Healthcare Pipeline

We’re imagining the future of healthcare by working to translate discovery into potentially meaningful outcomes for people with serious unmet medical needs. Click here to find out more about our Healthcare Pipeline.

Our People

Our people are courageous about advancing new science and passionate about delivering programs that make an impact on our communities. We strive for an inclusive and inspiring work environment, and year after year, our company achieves top survey results in terms of employee satisfaction and corporate culture.

We’re also growing our physical R&D footprint: Our new 160,000 square foot building is dedicated to the discovery of New Biological Entities and will be the fourth expansion of our campus in Billerica.

Find out more about joining a leading science and technology company.

“Working with my colleagues at the Boston R&D hub is so inspiring!

The drug hunting skills, the innovation, the energy and the cutting edge science all contribute to an extremely high level of productivity, which is in my mind second to none”.


Klaus Urbahns

Global Head of Discovery &
Development Technologies
EMD Serono Billerica Site Head


Why work for us

Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team means becoming part of a diverse, inclusive, and flexible working culture with great opportunities for personal development and career advancement across the globe.

Alongside our colleagues at Millipore Sigma and EMD Electronics, we've once again been named a "Top Place to Work" by the The Boston Globe in 2020. We also ranked #9 in the 2021 "Top Employers" survey conducted by Science Magazine.

What we do

We are Drug Hunters! With laboratories in Darmstadt, Tel Aviv, Boston, Guidonia, Ivrea and Japan, we work in close partnership with colleagues from the Therapeutic Innovation Platforms to deliver innovative and differentiated clinical drug candidates to our R&D pipeline.

What we do

Learn more about what we do and the kind of things you could be working on in each of our six departments


What we do

Comprising Structural Biology, Computational Chemistry & Biologics, and Drug Metabolism & Pharmacokinetics (DMPK), our 3D department prides itself on deep expertise in each of these disciplines. We bring this expertise to bear in our discovery and development projects, from concept to Life Cycle Management.

Our global labs and extensive partner networks are leveraged by our expert scientists to provide and interpret ADME data critical to optimizing our drug candidates. Whether in vitro, in vivo or simulation, we seek out innovative and predictive systems. We also create and execute DMPK strategies for small molecules and biologics in clinical development.

From crystal structures to sophisticated NMR and calorimetry experiments to atomic resolution cryo-EM studies, we provide and leverage detailed molecular interaction data for our drugs. Our computational scientists provide expertise to shape libraries, platforms, and tools for effective drug discovery. From FEP to Machine Learning, we seek to advances our discovery programs for all modalities including NCEs, NBEs, ADCs, degraders, and beyond.

Meet our team

Turn your curiosity into action and learn more about the different type of roles within our Discovery & Development Technologies (DDTech) teams
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Career opportunities

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What we do

Our team provides pharmacologically relevant, robust, and decision-critical in vitro biophysical, biochemical, and cellular data in a timely and economical fashion. Our data are major contributors to the characterization of targets and selection of pharmacological tool molecules and clinical candidates.

We support the advancement of all discovery projects by evaluation and integration of modern screening technologies. We employ efficient state-of-the-art laboratory automation and compound logistics towards the selection of clinical candidates.

Meet our team

Turn your curiosity into action and learn more about the different type of roles within our Discovery Pharmacology (DiscoPharm) teams.

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Career opportunities

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What we do

We design and synthesize new chemical entities that may become future therapies in neurology, immunology, and oncology. We support research projects from early stage (chemical biology-driven) to late stage (process chemistry-driven).

We deliver drug-like molecules by integrating our deep knowledge of synthetic organic chemistry with our practical familiarity with analytical chemistry, computational chemistry, pharmacology, pharmacokinetics, and structural biology. We leverage skills and strategies that enable us to deliver selective molecules for a multitude of target classes that are tailored to have mechanisms of action optimal for achieving the best balance of efficacy and tolerability.

Our team also uses state-of-the-art enabling technologies to design our molecules and execute our synthetic routes, including retrosynthetic software, in silico prediction software for toxicity and ADME properties, artificial intelligence platforms, flow chemistry, photochemistry, and electrochemistry.

Meet our team

Turn your curiosity into action and learn more about the different type of roles within our Medicinal Chemistry (MedChem) teams.

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Career opportunities

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What we do

We are a hybrid group of cell culture, purification, analytical, and cell line development scientists tasked with assessing developability of candidates and feasibility of new designs. Our roles include evaluating behavior of new drug candidates in our upstream and downstream platform processes, developing novel solutions, and supplying high quality proteins to our project teams.

Members of our group are also responsible for developing initial methods of characterization for our candidate molecules to support decision making, troubleshooting, and identify potential liabilities.

Meet our team

Turn your curiosity into action and learn more about the different type of roles within our Protein and Cell Sciences (PCS) teams.

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Career opportunities

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What we do

Our team leads the engineering of custom-made antibodies, bispecifics, complex antibody formats, and fusion proteins. This process often involves using state-of-the-art discovery technologies, functional screenings, microfluidics, and next generation sequencing.

Meet our team

Turn your curiosity into action and learn more about the different type of roles within our Protein Engineering and Antibody Technologies (PEAT) teams.
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Career opportunities

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What we do

We oversee the drug substance and drug product development for small molecules and clinical supply for NCE and NBE, covering early discovery stages, clinical development until launch, and post marketing activities like maintenance and life cycle management.

Our work often involves performing highly sensitive analytics, leveraging robust, efficient, and compliant manufacturing processes, and developing drug delivery technologies and formulations.

Meet our team

Turn your curiosity into action and learn more about the different type of roles within our Chemical & Pharmaceutical Development - Pharmaceutical Technologies (PharmTech) teams.
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Career opportunities

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Location

EMD Serono Research & Development Institute
45 Middlesex turnpike
Billerica, MA 01821

EMD Serono Building

Click here to learn more about our new WELL Certified Building.

Additional Company Information

Sustainability
For us, scientific progress and responsible entrepreneurship go hand in hand, enabling us to create a sustainable future for everyone.

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Diversity
We respect diversity and are committed to creating an inclusive culture that allows everyone to maximize their potential.

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Global Health
More than half the world’s population still does not have adequate access to healthcare. That’s why we have made it a high priority to address this global health challenge.

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