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Associate Scientist

Your Role:

We are seeking an Associate Scientist to be a part of the Virus and Gene Therapy Bioprocessing (VGTB) team.  The successful candidate will support the development of unit operations for Adeno-associated virus (AAV) and Lentivirus (LV) viral vector production utilizing the MilliporeSigma line of products.  This is a customer-facing process development group with expertise required in both upstream and downstream activities associated with viral vector manufacturing.  You will also provide input for areas of innovation and new product development to advance MilliporeSigma as the leader in viral vector bioprocessing.


As a member of the VGTB team, your responsibilities include the planning and execution of experimental designs using a DoE based approach, maintenance of adherent and suspension cell line used for gene therapy applications, bench and pilot scale virus production, analytical analysis for product quality/process recoveries, good documentation skills, and general lab maintenance duties.  This position requires a combination of intensive laboratory work, generation and delivery of scientific reports, and organization of documents.  The candidate will work in a matrix environment as a member of a highly dynamic team, working on multiple projects and contributing to the development of current and future cell-line engineering technologies and methods. 


Who You Are:

Minimum Qualifications:

  • Bachelor’s degree in Biology, Biochemistry, Biomedical Engineering or other scientific or engineering discipline
  • 1+ years’ experience with aseptic technique
  • 1+ years of mammalian cell culture experience


Preferred Qualifications:

  • 2+ years’ experience in product or process development for bioprocessing
  • 2+ years’ hands-on experience in Upstream or Downstream Bioprocessing unit operations and development and use of analytical assays
  • 1+ years’ experience in troubleshooting automated instrumentation and process equipment
  • Proficiency in molecular biology methods
  • Experience with LV and/or AAV viral vector production at pilot scales (up to 50L)
  • Experience designing experiments for and analyzing data from mammalian cell cultures in bioreactors
  • Knowledge and/or experience developing GMP processes
  • Knowledge of downstream unit operations (cell clarification, tangential flow filtration, and various chromatography systems) desired
  • Ability to exercise significant judgment when analyzing complex projects and demonstrate a high level of scientific achievement and understanding
  • Experience with various bioinformatic and office computer software systems.
  • Ability to thrive in a fast-paced team environment and the ability to work efficiently on challenging complex projects with aggressive timelines.
  • Excellent communication and organizational skills


Job Requisition ID:  199926
Location:  Bedford
Career Level:  C - Professional (1-3 years)
Working time model:  full-time

US Disclosure
The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.  This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

North America Disclosure
The Company is committed to accessibility in its workplaces, including during the job application process. Applicants who may require accommodation during the application process should speak with our HR Services team at 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday.

Nearest Major Market: Boston

Job Segment: Biochemistry, Biotech, Scientist, Product Development, Science, Research

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