Bioprocess Applications Engineer 3

Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 

Your Role

We’re seeking a Bioprocess Applications Engineer 3 to join the Single Use and Integrated Systems PAT & Digital Applications team, part of MilliporeSigma’s Process Solutions business unit. Based at our Bedford, MA campus, this role will support the development and application of integrated platform solutions for next-generation bioprocessing.

In this role, you will combine engineering fundamentals, hands-on experimentation, data analysis, modeling, and customer-focused problem-solving to evaluate emerging technologies and characterize system performance. You will translate application insights into product requirements, technical recommendations, and practical guidance that support both product development and customer success. Key responsibilities include:

• Integrate PAT sensors and inline spectroscopy into downstream unit operations, including Protein A chromatography, UF/DF, and other mAb purification steps
• Lead development, optimization, and lifecycle management of Raman chemometric models for mAb streams, buffers, and excipients
• Oversee qualification, deployment, and lifecycle support of Raman instruments and inline sensing units, including model transfer and qualification activities
• Identify and address customer PAT performance gaps, competitive technology landscapes, and process design targets through data-driven solutions and strategic recommendations
• Drive technical strategy in inline spectroscopy, advanced process control, and digitalization of process and analytical tools
• Lead cross-functional contributions spanning R&D, Manufacturing, Quality, Sales, and Product Management to commercialize PAT and digital solutions
• Produce customer-facing technical content, including application notes, technical guides, and webinars
• Support customer trials and investigations; capture actionable feedback to inform product and application development

Who You Are

Minimum Qualifications:

• Ph.D. in Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline

OR

• Master’s degree in Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline AND 4+ years of industry experience

OR

• Bachelor's degree in a Chemical Engineering, Mechanical Engineering, Biochemical Engineering or other engineering discipline AND 5+ years of industry experience

Preferred Qualifications:

• Experience in biopharmaceutical process development, PAT implementation, or analytical method development in a biomanufacturing context, with a demonstrated track record of leading technical projects to completion
• Technical expertise and hands-on experience with PAT sensors, inline spectroscopy (e.g., Raman), chemometric model development, process automation, and downstream biomanufacturing unit operations
• Experience leading projects of moderate to extended complexity, driving results and meeting milestones with excellent problem-solving skills, a collaborative mindset, and strong adherence to data integrity and cGMP documentation standards
• Ability to communicate effectively with peers, customers, vendors, and stakeholders through written technical reports, oral presentations, timely discussions and experience mentoring junior engineers
• Ability to apply engineering and scientific principles to resolve technical challenges of extended scope and complexity, with the ability to translate analytical insights into actionable process improvements and strategic recommendations

Pay Range for this position: $84,900 - $127,300 annually

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!