Share this Job

Head of Global DMPK

Your Role:

The Head of Global DMPK:

  • Leads the initiation and execution of Drug Metabolism and Pharmacokinetic (DMPK) aspects of drug projects at the company’s healthcare portfolio across all therapeutic modalities and indications.
  • Manages a world leading DMPK department globally. Ensure internal and external resources are fully engaged and developed.
  • Manages key external relations for the larger Discovery Technologies team and the company.
  • Creates the vision for DMPK and designs the long-term global strategy and operational model for the company’s healthcare research worldwide.
  • Ultimate decision-making for all issues associated with pharmacokinetic aspects of drug projects.
  • Creates a culture of innovation, entrepreneurship and global, collaborative working
  • Assigns resources and budget to all projects on a global basis. Ensures departmental performance in terms of quality clinical candidate delivery.
  • Accountable for cutting-edge infra-structure including laboratories, automation and robotics, design tools, electronic lab note-books and collaborative IT tools.
  • Initiates and leads external collaborations with major external scientific collaborators. Creates a climate of externalization and external innovation.
  • Resolves highly complex business and scientific problems through excellent scientific judgment and broad research, development and commercial knowledge. 
  • Chairs the global DMPK leadership team. Member of the the company Healthcare’s Discovery Research Committee and the Discovery and Development Technologies leadership team. 


Provides strategic impact through:

  • Generation the value of the company Healthcare’s clinical pipeline through quality candidate delivery.
  • Allocation of resources, setting strategies, priorities and policies, disseminating best practice and planning of the global DMPK Function.
  • Contribution to all in-licensing activities, including clinical-stage assets. 
  • Involvement to the strategy of drug discovery at the company. Predicts and preempts the company’s pipeline needs in all therapeutic areas.
  • Creation synergies and collaborates across the company’s functions beyond biopharma, e.g., Life Science division.


Who You Are:

  • Ph.D. and/or Post-Doc in drug metabolism, pharmacokinetics, analytical chemistry, synthetic organic chemistry, medicinal chemistry, protein engineering or immunology.
  • 10+ years in industry, at least 5 of which in managerial roles in R&D.
  • Ideally, experience in both small molecule and therapeutic proteins.
  • Demonstrated leadership experience in global organizations.
  • Strong track record of clinical candidate delivery and publications.
  • Experience in designing high performance DMPK organizations.
  • Experience in working with external partners.
  • Cross-divisional knowledge and awareness.  
  • Ability to travel internationally up 20% of the time.
  • Fluency in English.
Job Requisition ID:  188159
Location:  Billerica
Career Level:  E - Professional (10+ years)
Working time model:  full-time

Nearest Major Market: Boston

Job Segment: Immunology, R&D, Organic Chemistry, Healthcare, Research, Science

Apply now »