Senior Scientist - Protein Chemistry

Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 

Your Role:

EMD Serono in Billerica, MA is seeking a Senior Scientist – Protein Chemistry to add to their Oligonucleotide Therapeutics Group (DDTech).

Responsibilities:

• Perform protein/antibody expression, modification, purification, and characterization
• Design and engineer antibodies (vis Cysteine or Lysine engineering, enzymatic tagging or other site-specific strategies) to enable efficient conjugation
• Support SAR and collaborate closely with cross functional teams (Antibody Discovery, Oligonucleotide Chemistry, Analytical and Biology teams)
• Utilize knowledge of relevant assays - Binding (i.e. ELISA, SPR, BLI, flow cytometry), cell based (i.e. ADCC, CDC, proliferation) and biophysical characterization (i.e. stability, aggregation)

Who You Are: 

Minimum Qualifications:

• PhD in Biochemistry, Protein Chemistry, Computational Biology, Computer Science or other Science field
• 3+ years of industry experience in sequence and structure-based protein design

Preferred Qualifications:

• Good understanding of conjugation challenges like aggregation, charge effects, linker optimization and contribute to SAR Studies
• Familiarity with High throughput screening, AI/ML for antibody design
• Demonstrated experience with the state-of-the-art suite of tools for protein design and machine learning approaches (AlphaFold, ESM, ProteinMPNN, RF-Diffusion, Rosetta, etc.)
• Experience in leading and managing projects to ensure protein design relevant objectives are met on time and in high quality

• Experience with bispecific and multi-specific antibody platforms
• Excellent communication and problem-solving skills
• Ability to work independently

Pay Range for this position: $111,100 - $166,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!