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Associate Scientist II, In-vitro Cytogenetics II





In-vitro Cytogenetics II /Screening  lab runs a wide variety of GLP and Non GLP assays to characterize produce or material safety. Assays range from NGLP Screening Ames assays to in-vitro assays (NRU, BHAS, CHO Micronucleus FLOW, SHE, 3D Skin Comet).


Your role: The Associate Scientist II will perform a wide variety of assays or tests required to characterize product or material safety.



  • Conducts pre-designed assays using basic laboratory techniques and skills
  • Responsible for having a broad working knowledge of lab policies and assays
  • Independently conducts assigned test procedures within the constraints of laboratory scheduling
  • Follows Study Protocol, SOPs and relevant compliance regulations in regards to assay procedures, safety procedures, scientific responsibility and following GLP documentation, as applicable.
  • Independently analyzes data and interprets results
  • May be assigned R&D projects pertaining to the lab
  • Advises the Laboratory Supervisor of factors that may affect the quality and usefulness of the data
  • Maintains study workbooks and batch records
  • Uses and maintains scientific equipment, instrumentation and computer systems
  • Assists in training new staff members in performance of routine lab tasks
  • Demonstrates consistently good communication and interpersonal skills with employees, management and clients, where applicable
  • Contribute ideas and suggestions to improve standard laboratory techniques, protocols, processes and equipment
  • Use and maintain scientific equipment, instrumentation, and computer systems
  • Assist in writing/reviewing SOPs
  • Other duties as applicable and as assigned



  • Responsible for all phases of the NGLP Screening Ames assays (plate incorporation method, pre-incubation method, spot test method, and Ames II method); Comet Single Cell Gel Electrophoresis assay (preparation of slides, processing of organs, electrophoresis of slides, scoring of slides, and analysis of data); In Vitro Cytogenetic Micronucleus assays in CHO cells (seeding of cells, dosing of cells, washing of cells, harvesting/termination of cells and FLOW Analysis). Neutral Red Uptake Assay in BALB and CHO cells (seeding of cells, dosing of cells, washing of cells, harvesting/termination and scoring); Bhas 42 Cell Transformation assay (maintenance of cell cultures, plating the assay, scoring the assays by spectrophotometer or microscope); SHE Transformation assay; UDS Assay.



Who you are:  

An individual able to follow the SOPs, protocols and relevant compliance regulations in regards to safety procedures, documentation, and scientific responsibility and maintain an understanding of technological principles and applications of the organization’s services; independently analyze data, interpret results and advise the supervisor and study director of any factors that may affect quality and usefulness of data.


  • Education Level Required:
    • MA/MS in scientific discipline with no experience
    • BA/BS in scientific discipline with 1-3 years of experience
    • AA degree in scientific discipline with 4-6 years of experience
    • Or Equivalent scientific experience


  • Professional Skills, Qualifications and Experience
    • Working knowledge of a research laboratory.
    • Experience in cell/tissue culture and aseptic technique.


  • Travel Requirements
    • NA


  • Pre-Employment testing requirements
    • PFT and Hep B vaccine in addition to routing physical and blood work at Occupational Health Consultants


  • Physical Requirements (PPE, lifting)
    • Ability to use respirators


Job Requisition ID:  185553
Location:  Rockville
Career Level:  C - Professional (1-3 years)
Working time model:  full-time

Job Segment: Scientist, R&D, Laboratory, Research Scientist, Science, Research

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