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Senior Scientist/Team Leader

 

Your Role: The ideal candidate will lead a team to accomplish bio-conjugation process chemistry technology transfer and development campaigns designed to deliver robust and cost-effective production processes to GMP manufacturing.

 

ESSENTIAL JOB FUNCTIONS

  • Leverage experience in protein biochemistry and/or conjugation chemistry to on-board/develop, optimize and scale up bio-conjugation process chemistry unit operations.
  • Effectively work with key stakeholders to technology transfer time sensitive bio-conjugation production processes to GMP manufacturing.
  • Utilize experience in protein biochemistry for generic analysis and characterization of protein conjugates.
  • Troubleshoot bio-conjugate production process non-conformances and deliver data driven solutions

 

Who You Are:

 

Basic Qualifications:

 

  • Ph,D. Degree in biochemistry, biology or related field
  • Documented experience in protein or other biopolymer purification at both the bench and production scale employing state of the art chromatographic and ultrafiltration unit operations
  • Experience in bio-conjugation process chemistry development and optimization, including the use of Design of Experiments approaches highly desired
  • Documented experience in qualitative and quantitative characterization protein and/or bio-conjugate employing current and evolving analytical methods
  • Exemplary communication skills including timely and concise written and oral communications to both external and internal project stakeholders
  • Attention to detail in planning, execution and documentation of experimental work.

 

Preferred Qualifications:

 

  • 5+ years relevant experience in research and development in either industry or academia is preferred.
  • Experience related to chemical and/or enzymatic conjugation of small molecule payloads to biopolymer scaffolds strongly preferred.
  • Experience with protein purification, or oligo nucleotide purification on preparative scale a strong plus. 
  • Previous experience leading teams is highly desired.

 

 

Job Requisition ID:  185375
Location:  St. Louis
Career Level:  D - Professional (4-9 years)
Working time model:  full-time


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