PhD - Chemoproteomics Approaches In Drug Discovery (all genders)

Work Your Magic with us!  

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Your role

We are seeking a highly motivated PhD student to join our dynamic and expanding Proteomics team within the Discovery Pharmacology Department. You will work and improve on novel, innovative approaches for covalent drug discovery by means of (Chemo-)Proteomics for cellular target engagement (ABPP and other affinity-based methods), help in streamlining data analysis and explore methods for unlocking new target spaces beyond cysteine-engaging compounds. You will learn to operate and maintain a state-of-the-art proteomics infrastructure (Evosep ONE, TimsTOF MPP) and help in optimizing automated sample processing (HTS-lines; liquid-handler) as well as data acquisition strategies (DDA-/DIA-PASEF) for important aspects of early drug discovery. The PhD position is offered in collaboration with the Technical University of Munich AG Prof. Stephan Sieber and includes a short-term relocation to TUM in the first year for teaching and participation at the TUM Graduate School.

Who you are:

·         Graduate degree in (Organic-) Chemistry, Biotechnology, Pharmacy, or a related discipline.

·         Curious and analytical mindset.

·         Interest in MS-based proteomics (sample preparation, instrument operation, data analysis).

•    Capabilities in setting up data analysis and visualization tools e.g. with R and/or Python.

·         Excellent presentation and communication skills, both written and verbal. Fluent in English.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!